EVALUATION OF THE EFFICACY OF ANTIAGEING AND HYDRATING PRODUCTS ON THE CUTANEOUS SENESCENCE PROCESS. PRELIMINARY DATA
DIANA CRISAN1, MIRELA MOLDOVAN2*, IULIA BADEA3, RAMONA AVRAM3, ANDREA BOCA4, CARMEN MELINCOVICI5, CARMEN MIHU5, MARIA CRISAN5
University of Medicine and Pharmacy ”Iuliu Hatieganu” Cluj-Napoca
1Ulm University, Germany, Dermatology Intern
2Faculty of Pharmacy, Dermatopharmacy and Cosmetology Department
3Faculty of Medicine, Preventive Dentistry
4Faculty of Pharmacy, Pharmacology,Toxicology and Clinical pharmacology
5Faculty of Medicine, Histology Department
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During the last years, skin ageing and anti-ageing therapies have become an area
of increasing research interest. High frequency ultrasound allows the in vivo appreciation of
certain histological parameters and offers new characteristic markers, which may quantify
the severity of the cutaneous senescence process and efficacy of anti-ageing therapies. The
study presents some preliminary data regarding the effects of certain hydration and antiageing
products containing Viniferol, at cutaneous level. The changes in the dermal
echogenicity confirm the efficacy and direct action of Viniferol upon the cutaneous
fibroblasts. The anti-ageing therapy can be correlated with the age of the subjects and the
cutaneous phototype. The “critical age interval” involves specific changes in dermal
echogenicity that quantify intense molecular, biochemical and structural changes, being
thus mostly and highly responsive to the anti-ageing therapy.
Enlarged studies, on greater number of subjects are still necessary for the
standardization of the study method (high frequency ultrasound), regarding the efficacy of
the topically applied products.
