Romanian Society of Pharmaceutical Sciences
 

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EVALUATION OF THE ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF SAMBUCUS EBULUS EXTRACT

STELIANA RODINO1, ALINA BUTU2*, PETRUȚA PETRACHE1,3, MARIAN BUTU2, CRISTINA ELENA DINU-PÎRVU4, CĂLINA PETRUȚA CORNEA1

1.University of Agronomic Sciences and Veterinary Medicine, Bucharest, Bd Marasti 59, 011464, Romania
2 .National Institute of Research and Development for Biological Sciences, Splaiul Independentei 296, 060031, Bucharest, Romania
3 .EUROCIMPIA SRL, 117490, Mirosi, Arges
4 .“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Physical and Colloidal Chemistry Department, Traian Vuia 6, 020956, Bucharest, Romania

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This study investigated the inhibitory activity of Sambucus ebulus (danewort) fruit extract on the growth of several gram positive and gram negative bacteria, Bacillus subtilis, Enterococcus faecalis, Bacillus cereus, Staphylococcus aureus, Pseudomonas fluorescens, Escherichia coli and on the mycelial growth of some fungal pathogens, namely, Botrytis cinerea, Rhizoctonia solani and Phytophthora infestans. The contents of phenols, flavonoids and the antioxidant capacity were determined using spectrophotometric methods. The extract showed antimicrobial activity against most of the tested strains. The best results regarding antibacterial activity were obtained against P. fluorescens and E. fecalis.