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EFFICACY OF SALVIA MILTIORRHIZA EXTRACT INJECTION ON PERCUTANEOUS CORONARY INTERVENTION IN PATIENTS WITH CORONARY ATHEROSCLEROTIC HEART DISEASE

WEI LUO *, ZHAO XU, YI TANG

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Salvia miltiorrhiza extract, rich in salvianolic acid, has anti-inflammatory and microcirculatory benefits. This study evaluated its effects in coronary atherosclerotic heart disease (CAHD) patients’ post-percutaneous coronary intervention (PCI). One hundred patients were randomised into a control group (CG) receiving isosorbide dinitrate and an experimental group (EG) receiving Salvia miltiorrhiza extract in addition. EG showed a higher treatment success rate (92% vs. 74%) and greater improvements in heart rate, angina, cardiac function, lipid profile, endothelial function and cardiovascular biomarkers. Significant reductions were observed in LDL-C, troponin, CK-MB, hs-CRP, GDF-15 and GRACE scores, with better outcomes in the EG. Adverse events were fewer in the EG (p < 0.05). Salvia miltiorrhiza extract injection proved clinically effective in improving cardiovascular outcomes and reducing disease progression in CAHD patients after PCI.