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EFFECTS OF ROPIVACAINE ADMINISTRATION UNDER DIFFERENT OXYGEN CONCENTRATIONS ON PATIENTS UNDERGOING CESAREAN SECTION: A META-ANALYSIS

DONGYUN XIA, DANPING ZHENG *

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This meta-analysis evaluated the effects of ropivacaine under varying oxygen concentrations during caesarean section surgeries. A systematic review identified 12 relevant studies, categorizing participants into low-dose (LD) and high-dose (HD) ropivacaine groups. Data were analysed using RevMan 5.3 with fixed- or random-effects models. No significant differences were observed between HD and LD groups regarding surgical duration or anaesthesia duration. However, HD ropivacaine was associated with significantly higher neonatal Apgar scores. A high degree of heterogeneity was observed for sensory block duration, with the LD group showing notably shorter block duration. The findings indicate that oxygen concentration markedly affects ropivacaine's clinical performance in caesarean sections. HD ropivacaine provides enhanced anaesthesia, longer sensory block, better postoperative analgesia, and superior neonatal outcomes, supporting its preferential use in such surgical contexts.