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CONTRIBUTIONS TO THE PHARMACOGNOSTICAL AND PHYTOBIOLOGICAL STUDY OF FALLOPIA AUBERTII (L. HENRY) HOLUB. (POLYGONACEAE)

OCTAVIAN TUDOREL OLARU¹, ADRIANA IULIANA ANGHEL^*1, VIORICA ISTUDOR², ROBERT VIOREL ANCUCEANU¹, MIHAELA DINU¹

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In order to evaluate the therapeutic potential of the Faloppia aubertii (L.Henry) Holub (Russian vine) species for the use of the flowered aerial parts as raw material in the preparation of an active pharmacological extract, we decided to establish the microscopic characters, to identify the chemical constituents and to verify the cytotoxicity of this herbal product. The root and the stem are characterized by secondary structure with a well developed secondary xylem and sclerenchyma; the leaf blade - dorsi-ventral structure with two vascular bundles and calcium oxalate druses at the main vein, pluricellular glandular trichoma and anomocytic stomata within the epidermis; druses of calcium oxalate are present in all the organs examined. The following classes of phytochemicals were identified: carotenoids, flavonoids, sterols/triterpenes, polyphenol carboxylic acids, condensed tannins, polysaccharides, proanthocyanidins and reductive compounds. Through TLC (thin layer chromatography) analysis quercetin, kaempferol, myricetin, hyperoside, isoquercitrin, rutin and chlorogenic acid were identified. The 50% (w/v) aqueous and ethanolic solutions, with concentrations between 3.33% and 0.33%, presented cytotoxic activity (Constantinescu phytobiological method – Triticum bioassay).