Romanian Society of Pharmaceutical Sciences

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CHIRAL IONIC LIQUIDS IN CHIRAL ELECTROPHORETICAL SEPARATIONS

MIHAI STĂNESCU*, CORINA ARAMĂ, CRINA-MARIA MONCIU

Department of analytical chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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Chiral ionic liquids (CILs) are an important class of chiral selectors that in the last years gained a lot of importance. Their utility in several separation techniques and the relative simple synthesis, allowed them to have multiple applications. Capillary electrophoresis (CE) is an electromigration based technique allowing the analysis of smaller amounts of samples compared to other classical techniques, such as HPLC. Chiral ionic liquids are used in various chiral electromigration techniques for enantioselectivity improvement, since 2006. CILs are rarely used as unique chiral selectors, but some researchers focus on achieving this aim.