Romanian Society of Pharmaceutical Sciences
 

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CHEMICAL PROPERTIES OF SEVERAL RED WINES AVAILABLE ON ROMANIAN AND ALSO ON THE INTERNATIONAL MARKET

ERZSÉBET FOGARASI 1, MIRCEA DUMITRU CROITORU 1*, IBOLYA FÜLÖP 1, LUANA FALIBOGA 1, LAURIAN VLASE 2, ADRIANA JUNG 3, JUDIT HOHMANN 4, BILJANA BALABANOVA 5, VIOLETA IVANOVA-PETROPULOS 5, SASA MITREV 5, DANIELA-LUCIA MUNTEAN 6

1.University of Medicine and Pharmacy Tîrgu Mureş, Faculty of Pharmacy, Department of Toxicology and Biopharmacy, 38 Gh. Marinescu Street, Târgu Mureş, Romania
2.“Iuliu Haţieganu” University of Medicine and Pharmacy, Faculty of Pharmacy, Department of Pharmaceutical Technology and Biopharmacy, 12 Ion Creangă Street, Cluj-Napoca, Romania
3.University of Medicine and Pharmacy Tîrgu Mureş, Institute of Legal Medicine, 38 Gh. Marinescu Street, Târgu Mureş, Romania
4.University of Szeged, Department of Pharmacognosy, Szeged, Eötvös u. 6, Hungary
5.University "Goce Delcev" of Stip, Faculty of Agriculture, Krste Misirkov No. 10-A, Stip, Republic of Macedonia
6.University of Medicine and Pharmacy Tîrgu Mureş, Faculty of Pharmacy, Analytical chemistry and analysis of medicines, 38 Gh. Marinescu Street, Târgu Mureş, Romania
*corresponding author: croitoru.mircea@umftgm.ro

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The aim of this study was to perform a phytochemical analysis of 28 red wines available on Romanian and also on the international market. The identification of 14 polyphenols and their quantitative analysis were performed by HPLC/ESI-MS (high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry). Resveratrol contents were determined by HPLC/APCI-MS (HPLC coupled online with atmospheric pressure chemical ionization). Total polyphenols and monomeric anthocyanins were assayed by Folin-Ciocâlteu and pH differential methods. The GC-FID (gas chromatography coupled with flame ionization detector) system was used for the volatile congeners determination. The content of 35 toxic metals was investigated using a Q-ICP-MS (Quadruple inductively-coupled-plasma mass spectrometer) analyses. Quality and quantity of polyphenols, volatile congeners and metal content varied greatly among cultivars, and from this point of view, several Romanian wine samples could be considered of high quality when compared with international brands.