Romanian Society of Pharmaceutical Sciences
 

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BACTERIAL PATHOGENS ISOLATED FROM SURGICAL SITE INFECTIONS AND THEIR ANTIBIOTIC SUSCEPTIBILITY

AIDA PETCA 1#, SILVIUS NEGOIȚĂ 2#, RĂZVAN-COSMIN PETCA 3#, ANDREEA BORISLAVSCHI 1*, IOANA GABRIELA CALO 1, VALENTINA GABRIELA POPESCU 4, RUXANDRA DIANA SINESCU 5

1Department of Obstetrics and Gynaecology, Elias University Emergency Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2 Department of Anaesthesiology and Critical Care, Elias University Emergency Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
3 Department of Urology, “Prof. Dr. Th. Burghele” Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy,
Bucharest, Romania
4 Department of Vascular Surgery, Elias University Emergency Hospital, Bucharest, Romania
5 Department of Plastic Surgery & Reconstructive Microsurgery, Elias University Emergency Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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The increased reservoir of pathogenic bacteria sheltered in hospitals is the cause of various types of nosocomial infections and represents one of the major health problems. Surgical site infections (SSIs) count for 14 - 16% of all hospital-acquired infections (HAI) and represent the 3rd most occurring nosocomial infections and the 3rd most expensive HAI. We present a germ pattern (on 92 strains), located in post-operative dehiscence sites - treated with vacuum-assisted closure, in failed per secundam suture. The most common pathogens were E. coli – 18.47% (76.47% multi-drug resistant – MDR), Pseudomonas aeruginosa – 16.30% (33.33% MDR) and Enterococcus faecalis – 15.21%. Acinetobacter baumannii (100%) and Klebsiella pneumoniae (88.88%) also showed multi-drug resistance. Gentamicin, amikacin and carbapenems (> 50% sensibility) are eligible for treating SSIs, whereas cephalosporins have a higher resistance rate (> 50%). Knowledge of resistance patterns in SSIs is recommendable to ensure proper empirical treatment.