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ASSESSMENT OF AGE-RELATED CARDIOVASCULAR DISEASE USING REDOX STRESS MARKERS

CLAUDIA BĂCANU, DENISA MARGINĂ^*,, MIHAELA ILIE, NICULINA MITREA

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The general ageing of the population is considered one of the most important issues of the current medical research, several studies being devoted to finding the parameters that would allow a precise evaluation of the health status of the patients. Cardiovascular disease (CVD) is the main co-morbidity of the ageing process. Glycation of proteins and redox mechanisms are mainly involved in its development. In the present study we were focused on evaluating the level of advanced glycation end products (AGEs) as well as the susceptibility of serum lipids to induced peroxidation in samples from patients diagnosed with cardio-vascular disease compared to controls. Results show that the two evaluated markers are significantly increased in CVD patients.