Romanian Society of Pharmaceutical Sciences
 

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ANTIBIOTIC RESISTANCE PROFILE OF COMMON UROPATHOGENS IMPLICATED IN URINARY TRACT INFECTIONS IN ROMANIA

RĂZVAN-COSMIN PETCA 1#, RĂZVAN-IONUȚ POPESCU 1#, CRISTIAN MAREȘ 1#, AIDA PETCA 2*, CLAUDIA MEHEDINȚU 3, IULIA SANDU 1, NICOLETA MĂRU 4

1.Department of Urology, “Prof. Dr. Th. Burghele” Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
2.Department of Obstetrics and Gynaecology, Elias Emergency Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania2
3.Department of Obstetrics and Gynaecology, Malaxa Clinical Hospital, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
4.Department of Anatomy, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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Urinary tract infections (UTIs), the second most common type, are a healthcare problem encountered in medical practice, a major cause of morbidity with a high socio-economic impact. The aim of this retrospective study was to identify the most common uropathogens, their susceptibility and resistance to conventional therapies. We analysed the urine samples from 3896 patients and we enrolled 916 cases. Bacterial isolation and antibiotic susceptibility were made using standard methods. From the Gram-negative, E. coli was the most common identified bacteria (42.9%) followed by Klebsiella (21.17%) and Pseudomonas aeruginosa (4.58%). Enterococcus was the most frequent Gram-positive bacteria (18.66%). E. coli strains showed to have an increased resistance to levofloxacin as same as Klebsiella and Enterococcus. The continuous dynamic of uropathogens in different areas and the increasing resistance to conventional antibiotic therapies is a major contemporary health problem.