Romanian Society of Pharmaceutical Sciences
 

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THE STUDY OF QUALITY OF LIFE BEFORE AND AFTER ADMINISTRATION OF BOTULINUM TOXIN TO CHILDREN WITH CEREBRAL PALSY VERSUS CONTROL GROUP

IULIANA ŞTEFANIA DINU1, HOUSSEIN TOUFIC SEBLANY1*, MONICA SAFER2, DOINA ANCA PLEŞCA2

1.University of Medicine and Pharmacy „Carol Davila”, Dionisie Lupu 37 street, 2nd district, Bucharest
2 .Department of Pediatrics and Pediatric Neurology, „Victor Gomoiu” Children Clinical Hospital, University of Medicine and Pharmacy „Carol Davila”, Dionisie Lupu 37 street, 2nd district, Bucharest

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Cerebral palsy (CP) refers to a group of disorders in the development of motor control and posture, occurring as a result of a non-progressive impairment of the developing central nervous system. CP is a permanent disease which cannot be cured, but the consequences can be minimized and thus the negative impact can be reduced and the quality of life improved. Using Family Quality of Life Survey (FQOLS) – the version addressed to the main caregiver of the child with disability translated in Romanian language, the present study aimed to explore the quality of life (QoL) and to identify the areas of life that are affected for a CP child treated with botulinum toxin and child’s family compared to CP children who did not receive pharmacologic treatment, initially and after the follow-up period. The scores were statistically analyzed with the non-parametric Mann-Whitney U test for independent samples.