Romanian Society of Pharmaceutical Sciences
 

« Back to Farmacia Journal 6/2015

STUDY ON ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY AND PHENOLIC CONTENT OF ETHANOLIC EXTRACT OF HUMULUS LUPULUS

ANDREEA LETIȚIA ARSENE1, STELIANA RODINO2*, ALINA BUTU2, PETRUTA PETRACHE3, OVIDIU IORDACHE4, MARIAN BUTU2

1.Department of Biochemistry, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
2 .National Institute of Research and Development for Biological Sciences, Bucharest, Romania
3 .EUROCIMPIA SRL, Arges, Romania
4 .National Institute of Research and Development for Textile and Leather, Bucharest, Romania

Download Full Article PDF

The vegetal material is an inexhaustible source of biologically active compounds. It was already demonstrated that secondary metabolites of plant origin have practical application in the industry of food and beverage, drugs, and flavours. Furthermore, considering the acquired resistance of bacterial pathogens to existing antibiotics, research on new molecules of plant products is nowadays of great interest. Taking all these into consideration, we conducted a study on the inhibitory activity of Humulus lupulus L. (hops) extract against several gram negative and gram positive bacteria, (Bacillus subtilis, Enterococcus faecalis, Bacillus cereus, Staphylococcus aureus, Enterobacter cloacae, Pseudomonas fluorescens and Escherichia coli). The antimicrobial activity was performed by diffusion methods. The hops extract was also studied for its radical scavenging activity and total phenol content and total flavonoid content. The results obtained indicated that the hops extract could be used as raw material in the design of a plant based antimicrobial product.