Romanian Society of Pharmaceutical Sciences
 

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THE PREVALENCE OF INAPPROPRIATE USE OF NSAIDs BY CARDIOVASCULAR PATIENTS FOR MUSCULOSKELETAL DISORDERS

MARIA SUCIU 1#, LIANA SUCIU 1#, LAVINIA VLAIA 2*, MIRELA VOICU 1, VALENTINA BUDA 1, LIANA DRĂGAN 3, MINODORA ANDOR 4, VICENŢIU VLAIA 5, CARMEN CRISTESCU 1, MIRCEA HÎRJĂU 6

1.Department II – Pharmacology, Clinical Pharmacy, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
2.Department II – Pharmaceutical Technology, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
3.Department I – Drug Analysis, Environmental and Food Chemistry, Pharmaceutical Legislation, Management and Marketing, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
4.Department of Internal Medicine I – Medical Semiotics II, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
5.Department I – Organic Chemistry, “Victor Babeș” University of Medicine and Pharmacy, 2 Eftimie Murgu Square, 300041, Timișoara, Romania
6.Department of Pharmaceutical Technology and Biopharmacy , Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia Street, 020956, Bucharest, Romania

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A prospective observational analysis of the consumption of nonsteroidal anti-inflammatory drugs (NSAIDs)/paracetamol by cardiovascular (CV) patients over a 3-month period was performed. The aim of the study was to evaluate the potential inappropriate use of these drugs by CV patients and to identify the risk profile of the CV patient inclined towards self-medication with these molecules. The data obtained from the questionnaires completed by the respondents were statistically analysed using a SPSS statistical package (version 17.0) software. Our results showed that for both physicians and patients, the improvement of the patient’s symptoms and quality of life prevail over future CV risks. Our results indicate that despite existing warnings from the FDA and EMA, there is still a high percentage of CV patients who use NSAIDs inappropriately, both as self-medication and with medical advice, and the pharmacist must play a more active role in preventing the problems related to the irrational consumption of NSAIDs.