Romanian Society of Pharmaceutical Sciences
 

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THE IMPACT OF MIGRANT TUBERCULOSIS ON THE CHIMIORESISTANCE PATTERN OF ANTITUBERCULOSIS DRUGS IN A LOW BURDEN TUBERCULOSIS EUROPEAN COUNTRY

OANA-CRISTINA ARGHIR 1,2, PEDRO MANUEL ALVES PEREIRA 3, AGRIPINA RAȘCU 4*, ELENA DANTES 1,2, ERDIN BORGAZI 2, DAN MARCEL ILIESCU 1, MARINA RUXANDRA OȚELEA 4, SIMONA CLAUDIA CAMBREA 1

1.Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, 900527 Constanța, Romania;
2.Clinical Hospital of Pneumophthisiology, 40, Sentinelei Street, 900002 Constanța, Romania
3.Fellow-in Training Hospital de Faro, Algarve, Portugal
4.“Carol Davila” University of Medicine and Pharmacy Bucharest, Dionisie Lupu Street, sector 1, 030167, Bucharest, Romania

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The issue of drug resistance (DR) among patients with tuberculosis (TB) has occurred since the introduction of streptomycin and becomes a priority for TB control programs worldwide. Based on Portugal National Tuberculosis Surveillance System (SVIG-TB) and regional drug sensitivity testing (DST) database, a 10 year-epidemiological survey described retrospectively the impact of DR phenomenon on TB trend in Algarve, Portugal, from 01 January 2004 to 31 December 2014. Study sample included 106 patients with male (78%) and youth predominance. The most important risk factor for DR-TB consisted in immigration (31.13%).