Romanian Society of Pharmaceutical Sciences

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THE IMPACT OF HYPERTENSION AND ASSOCIATED COMORBIDITIES ON QUALITY OF LIFE ASSESSMENT QUESTIONNAIRE SF-36 V2

LIANA SUCIU1, CARMEN CRISTESCU1, MIRELA TOMESCU2, MELANIA BALAŞ3, RALUCA MUREŞAN4, VICENŢIU VLAIA5, MIRELA VOICU1, MARIA SUCIU1, RALUCA GRĂDINARU1, LAVINIA VLAIA*6, DOINA DRĂGĂNESCU7

1Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, University of Medicine and Pharmacy, Timişoara, Romania
2Department of Internal Medicine I, Faculty of Medicine, University of Medicine and Pharmacy, Timişoara, Romania
3Department of Endocrinology, Faculty of Medicine, University of Medicine and Pharmacy, Timişoara, Romania
4Department of Matematics, Faculty of Matematics and Informatics, West University Timişoara, Romania
5Department of Organic Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Timişoara, Romania
6Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Medicine and Pharmacy, Timişoara, Romania
7Department of Pharmaceutical Physics, Faculty of Pharmacy, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania

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Hypertension is a common cardiovascular disease insufficiently treated and monitored due to nonspecific symptomatology. Untreated hypertension causes cardiovascular complications: coronary artery disease, heart failure or stroke which, alongside other comorbidities affect the patients’ family, social and professional life [15]. Using SF-36 v2 quality of life assessment questionnaire, the present study aimed to analyze the influence the pathologies associated with hypertensive disease have on areas that make up its physical and psychosocial functions and its impact on patients' daily activities. This could help to improve the quality of health services in optimizing the adherence of the patients to the treatment. The study compared the quality of life indicators between the group of patients and a control group comprising healthy individuals. Comparing the scores obtained by the two groups, lower values in all subdomains were found for the study group compared with control group. The regression analysis showed that strong negative impact pathologies in all areas were heart failure, coronary heart disease, diabetes and anemia. The other pathologies differently influenced the physical and psychosocial functions.