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SYNTHESIS, SPECTRAL CHARACTERIZATION AND MOLECULAR DOCKING STUDIES OF NEW N3-ARYL- AND N3-ALKYL-BARBITURIC ACID DERIVATIVES WITH POTENTIAL LOCAL ANAESTHETIC ACTION
TEODOR OCTAVIAN NICOLESCU 1#, GABRIELA STANCIU 2#, MAGDALENA MITITELU 3#, ADINA MAGDALENA MUSUC 4*, LUCIAN ISCRULESCU 1, DRAGOȘ PAUL MIHAI 5, FLORICA NICOLESCU
1“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Organic Chemistry Department, 3-6 Traian Vuia Street, 020956, Bucharest, Romania
2“Ovidius” University of Constanța, Department of Chemistry and Chemical Engineering, 124 Mamaia Boulevard, 900527, Constanța, Romania
3“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Clinical Laboratory and Food Hygiene Department, 3-6 Traian Vuia Street, 020956, Bucharest, Romania
4“Ilie Murgulescu” Institute of Physical Chemistry, 202 Splaiul Independenței, 060021, Bucharest, Romania
5“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Pharmacology and Clinical Pharmacy Department, 3-6 Traian Vuia Street, 020956, Bucharest, Romania
6“Carol Davila” University of Medicine and Pharmacy, Faculty of Pharmacy, Toxicology Department, 3-6 Traian Vuia Street, 020956, Bucharest, Romania