Romanian Society of Pharmaceutical Sciences
 

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SYNTHESIS AND CHARACTERIZATION OF A NEW COMPLEX OF OXOVANADIUM (IV) WITH NARINGENIN, AS POTENTIAL INSULINOMIMETIC AGENT

VALENTINA UIVAROȘI1*, MIHAELA BADEA2, RODICA OLAR2, BRUNO ȘTEFAN VELESCU3, VICTORIA ALDEA1

1.Department of General and Inorganic Chemistry, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia, Bucharest, 020956, Romania
2.Department of Inorganic Chemistry, Faculty of Chemistry, University of Bucharest, 90-92 Panduri St., Bucharest, 050663, Romania
3.Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy, 6 Traian Vuia, Bucharest, 020956, Romania

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A new potentially biologically active complex of oxovanadium (IV) with naturally occurring flavanone naringenin has been synthesized and characterized in solid state by elemental analysis, molar conductance, UV-Vis spectra, FT-IR spectra, thermal analysis, and fluorescence spectra. From the experimental data, the complex was formulated as [VO(Nrg)2]·5H2O.