STATE-OF-THE-ART REVIEW ON IMPROVING TREATMENT ADHERENCE IN COPD BY TARGETING CONCURRENT PSYCHOLOGICAL SYMPTOMS
ELENA-ANDREEA MOALEȘ 1#, DOINA-CLEMENTINA COJOCARU 1,2, ANDREEA SILVANA SZALONTAY 1,3*, CRISTINA MIHAELA GHICIUC 1,4, MARCEL-ALEXANDRU GĂINĂ 1,3, DANIELA BOIȘTEANU 1,5, ANA MARIA FĂTU 1,6, MIHAI BOGDAN VÂSCU 1,7, SEBASTIAN COZMA 1,8, SILVIA ROBU 9#, FLORIN MITU 1,2, LUCIA CORINA DIMA-COZMA 1,2
1“Grigore T. Popa” University of Medicine and Pharmacy Iași, Romania 2Faculty of Medicine, Department of Medical Specialties I
3Faculty of Medicine, Department of Medical Specialties III
4Faculty of Medicine, Department of Morpho-Functional Sciences II 5Faculty of Medicine, Department of Medical Specialties III
6Faculty of Dentistry, Department of implantology, Removable Prosthesis, Dental Prosthesis Technology
7Faculty of Dentistry, Department of Odontology, Periodontology, Fixed Prosthesis
8Faculty of Medicine, Department of Surgery II
9“Dunărea de Jos” University,, Faculty of Medicine and Pharmacy, Department of Pharmaceutical Sciences, Galați, Romania
Download Full Article PDF
Chronic obstructive pulmonary disease (COPD), a condition with significant global impact, is characterised by progressive limitation of airflow, impaired lung structure and persistent respiratory symptoms. Anxiety and depression are the most common mental disorders in COPD patients and are associated with lesser treatment adherence. We conducted a literature search on PubMed, Cochrane Central Register of Controlled Trials, Web of Science and Scopus, up to July 1, 2022, regarding COPD anxiety and depression concurrence, an underlying mechanism such as hypoxemia, smoking, systemic inflammation and finally regarding pharmacological and alternative interventions that can raise treatment adherence of COPD patients through improving psychological outcomes. Acute dyspnoea, low body mass index, female gender, poor lung function, poor performance and regular smoking are risk factors for the association between depression and COPD. Pulmonary rehabilitation and telerehabilitation increase exercise tolerance and improve the mental status and patient-related outcomes. Psychotherapy and respiratory recovery significantly alleviate symptoms and increase the quality of life. Although more research is needed, immersive virtual reality facilitated interventions reveal promising results. Improving COPD patients’ treatment adherence should target concurrent psychological symptoms such as anxiety and depression.
