Romanian Society of Pharmaceutical Sciences

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REVIEW DIETARY AND PHARMACO-THERAPY IN SKIN DISEASES

IRINA MIHAELA MATRAN 1, ROXANA MARIA MARTIN-HADMAȘ 2*, CRISTINA NICULAȘ 3, DANIELA LUCIA MUNTEAN 4, MONICA TARCEA 2

1Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș,
Romania
2Department of Community Nutrition and Food Hygiene, Faculty of Medicine, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Romania
3Richter Pharmacy no 7, Cluj-Napoca, Romania
4Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy, “George Emil Palade” University of Medicine, Pharmacy, Science and Technology of Târgu Mureș, Romania

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Regardless of age and pathology, skin diseases are a public health problem, influencing the quality of patients’ life. Complementary to drug treatment, dietary treatment has been shown to be an effective adjunct in the amelioration or treatment of dermatological conditions. In this paper we aim to review the researches published in 2019 - 2022 on dietary treatment in skin diseases. Our study is a systematic review. The PubMed, Web of Science and NAMMDR (National Agency for Medicines and Medical Devices of Romania) databases were analysed. The search criteria were acne, allergic dermatitis, chronic urticaria and dietary treatment in skin diseases. There are numerous studies that demonstrate the importance and effectiveness of dietary treatment in dermatological pathology. For the acne vulgaris case, essential oil and bergamot juice, respectively those of sweet oranges, represent an effective dietary therapy by inhibiting the secretion of sebaceous glands and the release of IL-1α, stimulating apoptosis in the sebaceous glands. Other foods that are effective in treating skin diseases are: pasteurized and enhanced cow's milk with alkaline phosphatase, probiotics, Korean red ginseng or probiotics for atopic dermatitis. In the case of psoriasis, the effective dietary treatments are: curcumin, green tea, coffee, Calendula officinalis L, Origanum vulgare, Satureja hortensis L, Allium sativum, Anethum graveolens L. In the case of alopecia areata, the dietary treatment with ginger (Zingiber officinale) had very good results. Food supplements based on selenium, vitamins A, C, E, zing, manganese, copper and coenzyme Q10, are a variant with obvious clinical results in dermatology. Dietary treatment of skin diseases is a real complementary method. For high efficacy, due to the complexity of possible causes, the composition of foods or dietary supplements, as well as possible side effects, diagnosis and therapy must be approached multidisciplinary.