Romanian Society of Pharmaceutical Sciences

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RECOMMENDED STRATEGIES FOR PEMPHIGUS VULGARIS DIAGNOSIS AND MANAGEMENT IN ROMANIA

GEORGE SORIN ȚIPLICA 1,2#, IULIA ELENA NEGULEȚ 1,2*, IOANA SIMONA DINU 1,2#,
MIHAELA ȚOVARU 2,3#, BRANKA MARINOVIC 4, FREDERIC CAUX 5, AIKATERINI
PATSATSI 6, SNEJINA VASSILEVA 7, KOSSARA DRENOVSKA 7, ADRIAN LUCIAN BAICAN 8,
ALEXANDRA IRINA BUTACU 1,2, LAURA MARIA ENDRES 9, NICUȚA MANOLACHE 10,
CARMEN MARIA SĂLĂVĂSTRU 2,11

12nd Department of Dermatology, Colentina Clinical Hospital, Bucharest, Romania
2“Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
3Clinical Hospital of Infectious and Tropical Diseases “Dr. Victor Babeș”, Bucharest, Romania
4University Hospital Centre Zagreb, Zagreb, Croatia
5Department of Dermatology and Referral Centre for Autoimmune Bullous Diseases, Avicenne University Hospital,
Hôpitaux Universitaires de Paris Seine-Saint-Denis, Bobigny, France
6Autoimmune Bullous Diseases Unit, 2nd Dermatology Department Aristotle University School of Medicine Papageorgiou General Hospital Thessaloniki, Greece
7Sofia Univesity of Medicine, Sofia, Bulgaria
8Department of Dermatology, “Iuliu Hațieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania 9Pelican Clinical Hospital, Oradea, Romania
10“Anton Cincu” Municipal Hospital, Tecuci, Romania
11Pediatric Dermatology, Colentina Clinical Hospital, Bucharest, Romania

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Pemphigus belongs to autoimmune blistering diseases and affects the skin and/or mucous membranes with a potentially fatal outcome in untreated patients. The main type is represented by pemphigus vulgaris (PV) which accounts for 70% of all cases in Europe. The diagnosis and management of PV in Romania are challenging due to lack of official treatment guidelines, the treatment being based on different protocols of each medical unit. This paper aims to adjust the diagnosis and management of PV in Romania according to the existing and accepted international guidelines.