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OPTIMIZATION OF A FLOW CYTOMETRY PROTOCOL FOR PD-1/CTLA-4 IMMUNE CHECKPOINTS RECEPTORS DETECTION IN COLORECTAL CANCER TUMOUR MICROENVIRONMENT
MARIUS ZAMFIR 1,2, ARIANA HUDIȚĂ 3, MARA MARDARE 1,2, IRINA BONDOC 2, ANDREI VĂCĂRAȘU 2, BOGDAN COSMIN TĂNASE 2, GEORGE TRAIAN ALEXANDRU BURCEA-DRAGOMIROIU 4, MIRCEA LIȚESCU 5, THEODOR VOIOSU 6, BIANCA GĂLĂȚEANU 3*, CLAUDE LAMBERT 7, OCTAV GINGHINĂ 2,8
1Doctoral School of Medicine, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
2Department of Surgery 3, “Prof. Dr. Al. Trestioreanu” Institute of Oncology Bucharest, Romania
3Department of Biochemistry and Molecular Biology, University of Bucharest, Bucharest, Romania
4Department of Drug Control, Faculty of Pharmacy, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
5Department of Surgery, “Sf. Ioan” Clinical Emergency Hospital, Bucharest, Romania
6Department of Gastroenterology, Colentina Clinical Hospital, Bucharest, Romania
7Immunology lab, Central University Hospital, Saint-Etienne, France
8Department II, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy Bucharest, Romania