Romanian Society of Pharmaceutical Sciences

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NEW APPROACHES FOR ELECTROCHEMICAL DETECTION OF ASCORBIC ACID

MIHAELA BADEA 1#, SABINA CHIPEREA 1#, MIHAELA BĂLAN 1#, LAURA FLOROIAN 1#, PATRIZIA RESTANI 2#, JEAN-LOUIS MARTY 3#, CIPRIAN IOVAN 4#*, DELIA MIRELA ŢIŢ 5#, SIMONA BUNGĂU 5#, NICOLETA TAUS 1#

1.Transilvania University of Braşov, Faculty of Medicine, 56 Nicolae Bălcescu Street, Braşov, Romania
2.Universita Degli Studi di Milano, School of Pharmacy, 7 Via Festa del Perdono Street, Milano, Italy
3.University of Perpignan Via Domitia, Institut Universitaire de Technologie de Perpignan, Département Génie Biologique, Chemin de la Passio Vella - B.P 79905 66962, cedex 9, Perpignan, France
4.University of Oradea, Faculty of Medicine and Pharmacy, Department of Preclinical Sciences, 10 P-ţa 1 Decembrie Square, Oradea, Romania
5.University of Oradea, Faculty of Medicine and Pharmacy, Pharmacy Department, 29 Nicolae Jiga Street, Oradea, Romania
*corresponding author: dr.iovan@biostandard.ro
#All the authors have equal contribution at this original article.

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Ascorbic acid, well known as vitamin C, acts as antioxidant, helping the prevention of cell damage caused by free radicals. The paper presents fast methods for detecting ascorbic acid, using differential pulse voltammetry in different designed experiments. There were studied the possibilities of detection using buffer systems with pH 5.8, 7.0, 7.4 and original transducers. Each compound was analysed specifically at the potential indicated by the maximum signal appeared during the electrochemical study. The method could be successfully applied for single compound detection in food and drug samples.