Romanian Society of Pharmaceutical Sciences
 

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NEUROIMUNOTOXICITY OF ALUMINUM

CARMEN ADELLA SIRBU1, OCTAVIAN MIHAI SIRBU2*, CAMELIA CONSTANTIN3, ANCAMARIA SANDU2

1.Central Universitary Emergency Military Hospital “Carol Davila”, Department of neurology, Calea Plevnei Street 134, Bucharest, Romania
2.University of Medicine and Pharmacy, Faculty of General Medicine, Eroii Sanitari Street 8, Bucharest, Romania
3.Central Universitary Emergency Military Hospital “Carol Davila”, Department of ophthalmology, Calea Plevnei Street 134, Bucharest, Romania

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Aluminium (Al), abundant in Earth's crust, but not found in biochemical systems of plants, animals and humans become increasingly widely used because of its properties. Al accumulates in the body in different ways from various sources such as food, cosmetics, water, vaccines, in the latter being used as an adjuvant. The scientific world brings more and more data about the negative effects on humans and animals, both to the nervous system and to the immune system. Neurotoxic and immunotoxic effects are correlated with genetic susceptibility, thus explaining their relatively low incidence.