MICROBIOLOGICAL PROFILE AND ANTIBIOTIC RESISTANCE PATTERN OF BACTERIAL UROPATHOGENS AMONG HOSPITALIZED PATIENTS
ANDREEA-LOREDANA GOLLI 1, FLOAREA MIMI NIȚU 1, MARIA BĂLĂȘOIU 1, STEFAN RASCU 2*, MARINA ALINA LUNGU 3, SORIN NICOLAE DINESCU 1, LAVINIA CIOBANU-MITRACHE 3, ADINA GLODEANU , MIRELA VĂCARU 3, MIHAI OLTEANU 1
1.University of Medicine and Pharmacy Craiova, Str. Petru Rareş, nr. 2, Craiova, Romania
2.University of Medicine and Pharmacy Carol Davila, Bucuresti
3.County Emergency Clinical Hospital Craiova, str. Tabaci nr.1, Craiova, Romania
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Urinary tract infection (UTI) is the second most common type of infection and it may be a cause of considerable morbidity in case of recurrence. The aim of this retrospective study was to determine the distribution of pathogens involved in UTIs in hospitalized patients and their drug resistant pattern. It was analysed the distribution of the uropathogens from 427 urine samples collected from hospitalized patients from the urology clinic of County Emergency Clinical Hospital Craiova, between January to December 2017. Identification of the bacterial strains was performed on Chromagar (Oxoid) and the Vitek 2 Compact systems. The most common causative pathogens in UTIs were E. coli (45.35%), followed by Klebsiella spp., Enterococcus spp., Enterobacter spp. (8.18%). The strains of Enterobacteriaceae presented a high resistance to second and third generation cephalosporin, fluoroquinolones, and amoxicillin-clavulanic-acid. Surveillance of antibiotic prescription and monitoring studies are required to reduce the risk of drug resistance in bacterial uropathogens.