Romanian Society of Pharmaceutical Sciences

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LC-MS ANALYSIS AND ANTIOXIDANT ACTIVITY OF PHENOLIC COMPOUNDS FROM TWO INDIGENOUS SPECIES OF MENTHA. Note I

DANIELA BENEDEC1, LAURIAN VLASE1*, ILIOARA ONIGA1, AUGUSTIN C. MOT2, RADU SILAGHI-DUMITRESCU2, DANIELA HANGANU1, BRÎNDUŞA TIPERCIUC1, GIANINA CRIŞAN1

1Faculty of Pharmacy, “Iuliu Hatieganu” University of Medicine and Pharmacy, 12, I. Creanga Street, Ro-400023 Cluj-Napoca, Romania
2Department of Chemistry and Chemical Engineering University, Cluj-Napoca, Romania

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Two indigenous species of Mentha: M. viridis L. var. crispa (Schard.) Briq. and M. longifolia (L.) Huds. were studied in order to evaluate the phenolic profile and the natural antioxidant capacity. The polyphenolic content was determined by using the Folin- Ciocalteu reagent. The antioxidant activity was evaluated using 2,2-diphenyl-1- picrylhydrazyl (DPPH) radical scavenging assay. The determination of polyphenolic compounds was performed by HPLC-MS. In M. viridis var. crispa. aerial parts extract the phenolic acids were predominant, while in M. longifolia extract, the flavonoids were majoritary. These two extracts contain a large amount of phenolic compounds, and show moderate antioxidant activity.