Romanian Society of Pharmaceutical Sciences
 

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EFFECTS OF A PROTEIC SWINE EXTRACT ASSOCIATED TO RECOVERY TREATMENT ON FUNCTIONAL INDEPENDENCE AND QUALITY OF LIFE IN PATIENTS POST STROKE

DIANA UIVAROŞAN 1#, MOHAMED M. ABDEL-DAIM 2,3#, LAURA ENDRES 1#, LAVINIA PURZA 4,5#, CIPRIAN IOVAN 1#*, SIMONA BUNGĂU 5#, CRISTIAN GHEORGHE FURĂU 6#, DELIA MIRELA ŢIŢ 5#

1.University of Oradea, Faculty of Medicine and Pharmacy, Department of Preclinical Sciences, 10 P-ţa 1 Decembrie Street, Oradea, Romania
2.Suez Canal University, Faculty of Veterinary Medicine, Pharmacology Department, Ismailia 41522, Egypt
3.Yokohama City University, Department of Ophthalmology and Micro-Technology, Yokohama, Japan
4.University of Oradea, Doctoral School of the University of Oradea, Department of Biomedical Sciences, 1 Universităţii Street, Oradea, Romania
5.University of Oradea, Faculty of Medicine and Pharmacy, Pharmacy Department, 29 Nicolae Jiga Street, Oradea, Romania
6.Western University “Vasile Goldiş” of Arad, Faculty of Medicine, Department of Life Sciences, 86 L. Rebreanu Street, Arad, Romania

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Stroke is one of the leading causes of mortality and morbidity worldwide. This study investigates the effect produced by associating a proteic swine extract (PSE) with classical recovery techniques on functional independence and quality of life of post-stroke patients. 139 patients that had suffered stroke were divided into 2 groups and were evaluated initially, at 6 and at 12 months. The FIM scale (Functional Independence Measure) and the SS-QoL scale (Stroke Specific Quality of Life Scale), were used to monitor the effects of therapy. There were no significant differences (p > 0.05) in the patients′ evolution in terms of functional independence, but the effect size was more obvious in the group treated with PSE. The evolution of the quality of life was significantly better (p < 0.05) after six months for patients who had PSE associated treatment. The results of this study provide a favourable evidence for the use of associated therapy of PSE and classical recovery procedures in patients who had suffered a stroke.