Romanian Society of Pharmaceutical Sciences
 

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CHROMATOGRAPHIC ANALYSIS AND ANTIBACTERIAL POTENTIAL OF EXTRACTS OF GNETUM AFRICANUM

CRISTIAN SEBASTIAN VLAD 1, LAVINIA VLAIA 2, VICENŢIU VLAIA 2, VICTOR DUMITRAŞCU 1, MARIOARA NICOLETA FILIMON 3*, ROXANA POPESCU 4, ADINELA CIMPORESCU 5, CRISTINA DEHELEAN 2, CHINYERE EZINNE ONWUBIKO 6, CRISTINA VLAD DALIBORCA 1

1.“Victor Babeş” University of Medicine and Pharmacy, Faculty of Medicine, Pharmacology Department, 2 Eftimie Murgu Square, 300041, Timisoara, Romania
2.“Victor Babeş” University of Medicine and Pharmacy, Faculty of Pharmacy, 2 Eftimie Murgu Square, 300041, Timişoara, Romania
3.West University of Timişoara, Faculty of Chemistry, Biology, Geography, Biology-Chemistry Department, 16 Pestalozzi, 300115, Timişoara, Romania
4.“Victor Babeş” University of Medicine and Pharmacy, Faculty of Medicine, Cell and Molecular Biology Department, 14 Tudor Vladimirescu, 300173, Timişoara, Romania
5.Emergency Clinical Hospital “Pius Brinzeu”, Toxicology Department, 156 Liviu Rebreanu, 300723, Timişoara, Romania
6.Cardiotim Hospital, 6 Franyó Zoltán, 300014, Timişoara, Romania

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Traditionally, Gnetum africanum is being used widely for its nutritional value. In the present study, extracts of these plants were evaluated for their antimicrobial activity against some human pathogenic bacteria viz. S. aureus, B. cereus, E. coli, Klebsiella spp. and Enterobacter aerogenes. Gas-chromatographic results evidenced the presence of various bio-active compounds and the extracts applied on human pathogenic bacteria presented antibacterial effect, depending on the type of solvent used for the extraction and also the bacterial strain of concern, exception was made by the chloroformic extract which did not exhibit any antibacterial effect on the bacterial strains selected in the study.