CHOLINERGIC MODULATION OF MEMORY
RALUCA ELENA MOISESCU 1#, ISABEL CRISTINA VIORICA GHIȚĂ 1#*, ADELINA SORESCU 1#, OANA ANDREIA COMAN 1#, LAURENȚIU COMAN 2#, ION FULGA 1#
“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine
1.Department of Pharmacology and Pharmacotherapy
2.Department of Physiology
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Memory development is defined as the ability to encode, store and access new information. Certain neurotransmitters, but most importantly the cholinergic transmission via nicotinic receptors, have been linked not only to memory formation but to attention and other cognitive processes as well. In order to analyse previous literature on this subject a PubMed search was performed and it concluded 63 articles. We determined the overall efficacy and the prevalence of specific tests used. The implication of the cholinergic transmission via nicotinic receptors in memory has been well established over the years. Since the evolvement of technology, the nicotinic receptors have been linked not only to normal cognitive functions, but to the pathophysiology of certain neurodegenerative diseases as well. Due to their important roles in cognition, further studies need to be performed in order to determine their potential therapeutic effects.