Romanian Society of Pharmaceutical Sciences

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CHEMICAL COMPOSITION OF THE TUNISIAN NIGELLA SATIVA. NOTE II. PROFILE ON FATTY OIL

CLAUDIA-CRINA TOMA1*, GEORGETA MARIA SIMU2, DANIELA HANGANU3, NELI OLAH4, FLORINA MARIA GEORGIANA VATA5, CYRINE HAMMAMI6, MOHAMED HAMMAMI6

1Department of Pharmacognosy, Faculty of Pharmacy, "Vasile Goldis" West University of Arad, 1 Feleacului Street, 300041, Romania
2 Institute of Chemistry Timisoara of the Romanian Academy, B-dul Mihai Viteazul 24, 300223 Timişoara, Romania
3Department of Pharmacognosy, Faculty of Pharmacy, “Iuliu Haţieganu” University of Medicine and Pharmacy, Cluj – Napoca, 15 I.Creangă Street, Romania
4 Department of Pharmaceutical Industry, Faculty of Pharmacy, "Vasile Goldis" West University of Arad, 1 Feleacului Street, 300041, Romania
5Department of Toxicology, Faculty of Pharmacy, "Vasile Goldis" West University of Arad, 1 Feleacului Street, 300041, Romania
6Faculty of Medecine of Monastir, Venue Avicenne 5019, Monastir, Tunisia

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Nigella sativa L., Ranunculaceae, commonly named black cumin, is a spontaneous plant. Nigellae sativae semen has been used for a long time in the Arabian and Romanian ethnopharmacological field for its tonic effect. The scientific basis for using this plant was confirmed by phytochemical studies. These studies represent the scientifical confirmation of the empirical use of this vegetal product. The lipophylic fraction from Nigellae sativae semen contains, besides essential oils, fatty oils. The qualitative and quantitative analysis of fatty acids from mentioned oil were performed using GLC (Gas- Liquid Chromatography). The obtained fatty oil was found highly unsaturated, 84.35% from the total fatty acids representing the mono- and polyunsaturated fatty acids. The main fatty acid of the Tunisian Nigella sativa seeds was found the linoleic acid (C18:2) representing about 63.71% of the total fatty acids.