Romanian Society of Pharmaceutical Sciences
 

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BIOCHEMICAL DETERMINANTS OF AGGRESSIVE BEHAVIOUR – PATHO-PHYSIOLOGICAL CONNECTIONS IN ESRDAND DIALYSIS

IRINA NEGOESCU 1#, DAN ALEXANDRU NICULESCU 2,3#, CRISTIANA DAVID 4,5#, ILEANA PERIDE 4,5*#, ANDREI NICULAE 4,5#, IONEL ALEXANDRU CHECHERIȚĂ 4,5#, CĂTĂLINA POIANĂ 2,3#

1.PhD Student, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
2.Department of Hypophysis and Neuroendocrine Pathology, “C. I. Parhon” National Institute of Endocrinology, 34-38 Aviatorilor Boulevard, 011863, Bucharest, Romania
3Clinical Department No. 2, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, 020021, Bucharest, Romania
4.Department of Nephrology and Dialysis, “Sf. Ioan” Emergency Clinical Hospital, 13 Vitan-Barzesti Road, 042122, Bucharest, Romania
5.Clinical Department No. 3, “Carol Davila” University of Medicine and Pharmacy Bucharest, 37 Dionisie Lupu Street, 020021, Bucharest, Romania

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Violence and aggression are among the most important problems of the contemporary world. Modern humanity vices, like alcohol, drug abuse, daily stress, but also specific therapies within the positive tendency to prolong life in severe chronic diseases seems to contribute to the ascending trend of aggressive behaviour. A topic of debate is the ability of chronic kidney disease and its treatment to induce biochemical and behavioural changes that predispose to impulsivity. The answer can reveal treatment adjustments (chemical, procedural and psychological) that can be made for improving behavioural condition and the quality of life in these patients.