Romanian Society of Pharmaceutical Sciences

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ANTIOXIDANT AND ANTIMICROBIAL PROPERTIES OF CHRYSANTHEMUM AND TAGETES SELECTIVE EXTRACTS

ANA FLAVIA BURLEC 1#, OANA CIOANCA 1*, CORNELIA MIRCEA 1#, CRISTINA ARSENE 2, CRISTINA TUCHILUȘ 2#, ANDREIA CORCIOVĂ 1, MONICA HĂNCIANU 1

1.Faculty of Pharmacy, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania
2.Faculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy, 16 Universității Street, 700115, Iași, Romania

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The present study focuses on two ornamental species of the Asteraceae family and their biological properties, which can be correlated with the presence of different classes of natural compounds. Given the fact that secondary metabolites found in such plants can be used as valuable resources for the pharmaceutical industry, we chose to investigate the biological potential of Chrysanthemum indicum and Tagetes erecta inflorescences. Four types of extracts were obtained for each species, using organic solvents with different polarities. Bioactive compounds such as polyphenols were quantitatively analysed using a the Folin-Ciocâlteu method. The investigated compounds were present in all types of extracts in variable quantities, the highest amounts being found in the methanolic extracts. Positive dose-related values revealed that the investigated extracts exhibit good inhibitory activity against 15-lipoxygenase and a moderate metal-chelating activity. Moreover, all extracts showed promising antibacterial and antifungal activities on the tested strains.