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ACUTE TOXICITY ASSESSMENT OF GRAPTOPHYLLUM PICTUM (L.) GRIFF. LEAVES ETHANOLIC EXTRACT AND ITS NANOFORMULATIONS: COMPARATIVE STUDY OF PHYTOSOME AND CYCLODEXTRIN INCLUSION COMPLEX
IDHA KUSUMAWATI 1,2*, SUBHAN RULLYANSYAH 1, MEGA FERDINA WARSITO 3, MUHAMMAD ZDULQORNAIN 1, FIRDAUSYAH NURAINI 1, AISYAH FARAH RIZKA 1, YUSUF ALIF PRATAMA 1, RETNO WIDYOWATI 1, EKA PRAMYRTHA HESTIANAH 4, KATSUYOSHI MATSUNAMI 5
1Department of Pharmaceutical Science, Faculty of Pharmacy, Universitas Airlangga, Nanizar Zaman Joenoes Building, Jl.
Mulyorejo, Surabaya, 60115, East Java, Indonesia
2Natural Product Drug Discovery and Development Research Group, Faculty of Pharmacy, Universitas Airlangga, Nanizar
Zaman Joenoes Building, Jl. Mulyorejo, Surabaya, 60115, East Java, Indonesia
3Research Center for Applied Microbiology, National Research and Innovation Agency (BRIN), Komplek CSC-LIPI, Jl. Raya Bogor Km 46, Cibinong 16911, West Java, Indonesia
4Veterinary Anatomy Department, Faculty of Veterinary, Universitas Airlangga, Jl. Mulyorejo, Surabaya 60115, East Java, Indonesia
5Department of Pharmacognosy, Graduate School of Biomedical & Health Sciences, Hiroshima University 1-2-3, Kasumi, Minami-ku, Hiroshima, Japan