COMPARATIVE STUDY OF THE CLINICAL RESPONSE OF PATIENTS
TO DIFFERENT TREATMENT REGIMENS IN RHEUMATOID
ARTHRITIS
DIANA IOANA MANUELA TEAHA 1*, NICOLETA-ANAMARIA PAȘCALĂU 2, LIVIU LAZĂR 1
1Doctoral Studies Department, Biomedical Science, 1 University Street, Oradea, Romania
2Faculty of Medicine and Pharmacy, Department of Medicine-Psycho-Neuroscience and Recovery, 10 1st Decembrie Street,
Oradea, Romania
*corresponding author: dteaha@yahoo.com
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Abstract:
There are different therapeutic solutions available for rheumatoid arthritis (RA) patients, suitable for different stages and
different comorbidities. The outcome depends on both the patient's clinical response and the therapeutic treatment chosen.
The main clinical objectives are slowing the progression of disease and the effective management of patient symptoms,
avoiding as far as possible the irreversible damage on the joints and cartilages. In this study we observed four different
treatment strategies available and recommended in RA in terms of therapy response considering the stage of RA that the
patients were in, as well. The strategies involved, included methotrexate in monotherapy, methotrexate combined with
biological therapy, methotrexate and corticotherapy and methotrexate and physiokinetotherapy. Following this study, the
most efficient statistically in the treatment response, were the patients included in the group of methotrexate combined with
biological therapy.

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