ANTIOXIDANT, ANTIMICROBIAL AND PHOTOCATALYTIC
ACTIVITIES OF SILVER NANOPARTICLES OBTAINED BY BEE
PROPOLIS EXTRACT ASSISTED BIOSYNTHESIS
ANDREIA CORCIOVĂ 1#, CORNELIA MIRCEA 1*, ANA-FLAVIA BURLEC 1#, OANA CIOANCĂ 1, CRISTINA TUCHILUŞ 2#, ADRIAN FIFERE 3, ANA-LĂCRĂMIOARA LUNGOCI 3, NARCISA MARANGOCI 3, MONICA HĂNCIANU 1
1“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, 16 Universităţii Street, 700115, Iași, Romania
2“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, 16 Universității Street, 700115, Iași, Romania
3“Petru Poni” Institute of Macromolecular Chemistry, Center of Advanced Research in Bionanoconjugates and Biopolymers,
41A Grigore Ghica-Vodă Alley, 700487, Iaşi, Romania
*corresponding author: corneliamircea@yahoo.com
#Authors with equal contribution
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Abstract:
Taking into consideration the advantages of green synthesis of nanoparticles, the present study focuses on the formation,
characterization and evaluation of some biological activities of silver nanoparticles (AgNPs) obtained using bee propolis
extract. The total phenolic and total flavonoid contents were evaluated. The formation of AgNPs was primarily confirmed by
the change in colour and by the appearance in the UV-Vis spectrum of the characteristic silver surface plasmon resonance
band. Several compounds that can participate in the reduction process were identified by characteristic peaks of functional
groups in the FTIR spectra. The presence of elemental silver was confirmed by Energy-dispersive X-ray (EDX)
spectroscopy. Morphological study of AgNPs was carried out using Transmission electron microscopy (TEM) and confirmed
the spherical shape. The investigated propolis extract is a valuable source of compounds which can participate in the
synthesis of AgNPs with antimicrobial, antioxidant and photocatalytic degradation properties.

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