EVALUATION OF ANTI-INFLAMMATORY AND ANALGESIC
ACTIVITY OF THE AQUEOUS METHANOLIC EXTRACT OF
ASPRARAGUS RACEMOSUS IN EXPERIMENTAL MODELS
HASEEB AHSAN 1*, IHTISHAM HAIDER 2, MUHAMMAD NAVEED MUSHTAQ 3, IRFAN ANJUM 3
1College of pharmacy, University of Sargodha, Sargodha, Pakistan
2Nawaz Sharif medical college, University of Gujrat, Pakistan
3Faculty of Pharmacy, Department of Pharmacology, The University of Lahore, Lahore, Pakistan
*corresponding author: haseeb.ahsan@uos.edu.pk
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Abstract:
The aim of the present study was to evaluate the anti-inflammatory and analgesic activity of the aqueous methanolic extract
of the root of Asparagus racemosus in Albino mice model. Oedema models were induced by injection of carrageenan and
fresh egg albumin into right hind paw. Acetic acid and formalin were used to induce pain models. The aqueous methanolic
extract showed significant reduction in both paw oedema models. In pain models, the extract also significantly inhibited the
acetic acid-induced writhing and formalin-induced paw lickings. Our findings showed that aqueous methanolic extract of
Asparagus racemosus’s root reduced inflammation and pain in experimental models. The results proposed a potential use of
Asparagus racemosus’s roots in treating conditions associated with inflammation and pain.

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