MICROBIOLOGICAL PROFILE AND ANTIBIOTIC RESISTANCE
PATTERN OF BACTERIAL UROPATHOGENS AMONG HOSPITALIZED
PATIENTS
ANDREEA-LOREDANA GOLLI 1, FLOAREA MIMI NIȚU 1, MARIA BĂLĂȘOIU 1, STEFAN RASCU 2*, MARINA ALINA LUNGU 3, SORIN NICOLAE DINESCU 1, LAVINIA CIOBANUMITRACHE 3, ADINA GLODEANU 1, MIRELA VĂCARU 3, MIHAI OLTEANU 1
1University of Medicine and Pharmacy Craiova, Str. Petru Rareş, nr. 2, Craiova, Romania
2University of Medicine and Pharmacy Carol Davila, Bucuresti
3County Emergency Clinical Hospital Craiova, str. Tabaci nr.1, Craiova, Romania
*corresponding author: stefanrascu.sr@gmail.com
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Abstract:
Urinary tract infection (UTI) is the second most common type of infection and it may be a cause of considerable morbidity in
case of recurrence. The aim of this retrospective study was to determine the distribution of pathogens involved in UTIs in
hospitalized patients and their drug resistant pattern. It was analysed the distribution of the uropathogens from 427 urine
samples collected from hospitalized patients from the urology clinic of County Emergency Clinical Hospital Craiova,
between January to December 2017. Identification of the bacterial strains was performed on Chromagar (Oxoid) and the
Vitek 2 Compact systems. The most common causative pathogens in UTIs were E. coli (45.35%), followed by Klebsiella
spp., Enterococcus spp., Enterobacter spp. (8.18%). The strains of Enterobacteriaceae presented a high resistance to second
and third generation cephalosporin, fluoroquinolones, and amoxicillin-clavulanic-acid. Surveillance of antibiotic prescription
and monitoring studies are required to reduce the risk of drug resistance in bacterial uropathogens.

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