INVESTIGATION OF ANTIBIOTIC SUSCEPTIBILITY OF THE
BACTERIAL ISOLATES AND LOCAL FLORA CHANGES AFTER
COMPLEX THERAPY IN CHRONIC PERIODONTITIS AND
PERIIMPLANTITIS
LIDIA CIOBANU 1#, GABRIELA BĂNCESCU 1#*, ANDREEA CRISTIANA DIDILESCU 2#, ADRIAN ANTON BĂNCESCU 3#
1Department of Microbiology, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
2Department of Embryology, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
3Department of Epidemiology, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania
*corresponding author: gabi.bancescu@gmail.com
#All authors have equal contribution
Download Full Article

Abstract:
The aim of the study was to test the antibiotic susceptibility of the subgingival biofilm (SGBF) isolates from chronic
periodontitis (PD) and periimplantitis (PI) sites, and to investigate the changes of local flora after complex therapy including,
amoxicillin-clavulanate (XL). SGBF from periodontal pocket (A sample) and around the dental implant (B sample) was
collected before (t1) and after (t2) therapy. Gram smears and cultures on blood media were done. E-test was used for the
antibiotic susceptibility testing. The smears indicated at t2 a significant decrease of polymorphonuclears number and
microbial load with marked reduction of spirochetes and Gram-negative bacilli number. In A sample, P. intermedia and
Capnocytophaga predominated at t1 and S. oralis at t2, while in B sample, Capnocytophaga predominated at t1 and S. mitis at
t2. All except 2 isolates (not recovered at t2) were XL-susceptible. The clinical and microbiological findings showed local
status improvement at t2. The antibiogram is helpful when antibiotics are needed in PD/PI therapy.

Top