FOODS AND FOOD GROUPS ASSOCIATED WITH COLORECTAL
CANCER: A CASE-CONTROL STUDY
LAURA IOANA GAVRILAȘ 1, CORINA IONESCU 2, OVIDIU BĂLĂCESCU 3, CORNELIA REVNIC 4, DANIELA CIOBÂRCĂ 1, LORENA FILIP 1, ANAMARIA BOBOIA 5*, DOINA MIERE 1
1Department of Bromatology, Hygiene, Nutrition, “Iuliu Haţieganu” University of Medicine and Pharmacy, 23 Marinescu
Street, Cluj-Napoca, Romania
2Department of Pharmaceutical Biochemistry and Clinical Laboratory, “Iuliu Haţieganu” University of Medicine and
Pharmacy, 6 Louis Pasteur Street, Cluj-Napoca, Romania
3Department of Functional Genomics, Proteomics and Experimental Pathology, The Oncology Institute “Prof. Dr. Ion
Chiricuţă”, 34-36 Republicii Street, Cluj-Napoca, Romania
4Department of Mathematics-Informatics, “Iuliu Haţieganu” University of Medicine and Pharmacy, 6 Louis Pasteur Street
400349, Cluj-Napoca, Romania
5Department of Pharmaceutical Management, Marketing and Legislation, “Iuliu Haţieganu” University of Medicine and
Pharmacy, 8 Victor Babeş Street, 400012, Cluj-Napoca, Romania
*corresponding author: aboboia@umfcluj.ro
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Abstract:
Dietary habits act as important determinants of cancer risk and are especially associated with colorectal cancer (CRC), one of
the most important diet-related types of cancer. In this regard, the main goal of the present study was to investigate the risk
and protective dietary factors related with CRC in Romanian population. A case-control study was conducted from August
2015 until January 2017. Data was collected from cancer-free controls (n = 151) and CRC cases (n = 151) using a food
frequency questionnaire. The questionnaire was completed during a face-to-face interview led by a trained dietitian. The
results showed that intake of poultry, fish, and fibre-rich foods are inversely associated with CRC risk. Furthermore, dietary
habits linked with a Western diet such as high intake of processed meat, sugar-sweetened beverages, white bread and dessert
(p = 0.001) were more frequent in the CRC group.

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