EFFECTS OF A PROTEIC SWINE EXTRACT ASSOCIATED TO
RECOVERY TREATMENT ON FUNCTIONAL INDEPENDENCE AND
QUALITY OF LIFE IN PATIENTS POST STROKE

DIANA UIVAROŞAN 1#, MOHAMED M. ABDEL-DAIM 2,3#, LAURA ENDRES 1#, LAVINIA PURZA 4,5#, CIPRIAN IOVAN 1#*, SIMONA BUNGĂU 5#, CRISTIAN GHEORGHE FURĂU 6#, DELIA MIRELA ŢIŢ 5#
1University of Oradea, Faculty of Medicine and Pharmacy, Department of Preclinical Sciences, 10 P-ţa 1 Decembrie Street,
Oradea, Romania
2Suez Canal University, Faculty of Veterinary Medicine, Pharmacology Department, Ismailia 41522, Egypt
3Yokohama City University, Department of Ophthalmology and Micro-Technology, Yokohama, Japan
4University of Oradea, Doctoral School of the University of Oradea, Department of Biomedical Sciences, 1 Universităţii Street,
Oradea, Romania
5University of Oradea, Faculty of Medicine and Pharmacy, Pharmacy Department, 29 Nicolae Jiga Street, Oradea, Romania
6Western University “Vasile Goldiş” of Arad, Faculty of Medicine, Department of Life Sciences, 86 L. Rebreanu Street, Arad,
Romania
*corresponding author: dr.iovan@biostandard.ro
#All authors have equal contribution
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Abstract:
Stroke is one of the leading causes of mortality and morbidity worldwide. This study investigates the effect produced by
associating a proteic swine extract (PSE) with classical recovery techniques on functional independence and quality of life of
post-stroke patients. 139 patients that had suffered stroke were divided into 2 groups and were evaluated initially, at 6 and at
12 months. The FIM scale (Functional Independence Measure) and the SS-QoL scale (Stroke Specific Quality of Life Scale),
were used to monitor the effects of therapy. There were no significant differences (p > 0.05) in the patients′ evolution in
terms of functional independence, but the effect size was more obvious in the group treated with PSE. The evolution of the
quality of life was significantly better (p < 0.05) after six months for patients who had PSE associated treatment. The results
of this study provide a favourable evidence for the use of associated therapy of PSE and classical recovery procedures in
patients who had suffered a stroke.






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