COMPARATIVE STUDY OF ORAL ANTIDIABETIC THERAPY AND
INSULIN THERAPY ON HEPATIC STEATOSIS IN PATIENTS WITH
TYPE 2 DIABETES MELLITUS
ANICA HOZA, CORINA MOLDOVAN, DORINA MARIA FĂRCAȘ, ANNAMARIA PALLAG *, SEBASTIAN NEMETH, FELICIA MARC
Faculty of Medicine and Pharmacy, University of Oradea, Romania
*corresponding author: annamariapallag@gmail.com
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Abstract:
In type 2 diabetes mellitus (DM) patients, hepatic steatosis is present in a much higher proportion than in healthy people. In
this study, we have evaluated the presence of steatosis in patients with type 2 DM, and whether this may be correlated with
the type of treatment that patients are using, either with oral antidiabetics (OAD), or with insulin therapy +/- OAD. In the
same time, steatosis has been correlated with nutritional status, metabolic control, and lipidic profile. The results showed that
patients treated with insulin, exhibited hepatic steatosis in a statistically significant lower percent than patients treated with
OAD. This finding is maintained after the correlation with weight status or metabolic control.






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