THE IMPACT OF MIGRANT TUBERCULOSIS ON THE
CHIMIORESISTANCE PATTERN OF ANTITUBERCULOSIS DRUGS
IN A LOW BURDEN TUBERCULOSIS EUROPEAN COUNTRY
OANA-CRISTINA ARGHIR 1,2, PEDRO MANUEL ALVES PEREIRA 3, AGRIPINA RAȘCU 4*, ELENA DANTES 1,2, ERDIN BORGAZI 2, DAN MARCEL ILIESCU 1, MARINA RUXANDRA OȚELEA 4, SIMONA CLAUDIA CAMBREA 1
1Medicine Faculty, “Ovidius” University of Constanța, 124, Mamaia Blvd, 900527 Constanța, Romania;
2Clinical Hospital of Pneumophthisiology, 40, Sentinelei Street, 900002 Constanța, Romania
3Fellow-in Training Hospital de Faro, Algarve, Portugal
4“Carol Davila” University of Medicine and Pharmacy Bucharest, Dionisie Lupu Street, sector 1, 030167, Bucharest,
Romania
*corresponding author: agrirascu@yahoo.com
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Abstract:
The issue of drug resistance (DR) among patients with tuberculosis (TB) has occurred since the introduction of streptomycin
and becomes a priority for TB control programs worldwide. Based on Portugal National Tuberculosis Surveillance System
(SVIG-TB) and regional drug sensitivity testing (DST) database, a 10 year-epidemiological survey described retrospectively
the impact of DR phenomenon on TB trend in Algarve, Portugal, from 01 January 2004 to 31 December 2014. Study sample
included 106 patients with male (78%) and youth predominance. The most important risk factor for DR-TB consisted in
immigration (31.13%).

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