COMPARATIVE ASSESSMENT OF THE BENEFITS OF POTASSIUM
AND MAGNESIUM TRIBASIC CITRATE VERSUS TAMSULOSIN IN
NEPHROLITHIASIC PATIENTS
CĂTĂLIN PRICOP 1,2#, DRAGOŞ PUIA 1,2#*, DRAGOMIR ŞERBAN 1#, ILEANA PERIDE 3,4#, ANDREI NICULAE 3,4#, VIOREL JINGA 3,5#
1“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, 16 Universității Street, 700115, Iași, Romania
2“C. I. Parhon” Hospital, Department of Urology, 50 Carol I Boulevard, 700503, Iași, Romania
3“Carol Davila” University of Medicine and Pharmacy, Faculty of Medicine, Clinical Department No. 3, 37 Dionisie Lupu
Street, 030167, Bucharest, Romania
4“Sfântul Ioan” Emergency Clinical Hospital, Department of Nephrology and Dialysis, 13 Vitan-Bârzești Road, 042122,
Bucharest, Romania
5“Prof. Dr. Theodor Burghele” Clinical Hospital, Department of Urology, 20 Panduri Road, 050653, Bucharest, Romania
*corresponding author: drdragos83@yahoo.com
#All authors have equal contribution
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Abstract:
Nephrolithiasis is a major health issue. Present guidelines recommend conservative treatment for calculi less than 5 mm. Over
the years, various therapeutic regimens to facilitate spontaneous passage of stones have been used without reaching a consensus
in this respect. We aimed to compare the efficacy of potassium and magnesium tribasic citrate which has metaphylactic
indications with that of a selective alpha-blocker as medical expulsion therapy. The preliminary results of this ongoing study
showed that in patients with pelvic ureteric lithiasis, the alpha-blocker-based expulsion treatment was significantly more
effective than that based on potassium and magnesium tribasic citrate. As for asymptomatic lumbar ureteric lithiasis below 7
mm in diameter, the alpha-blocker and potassium and magnesium tribasic citrate treatment showed similar results.

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