THE IMPACT OF URAPIDIL USE IN HYPERTENSION PREHOSPITAL
EMERGENCY INTERVENTION
GABRIELA PRODAN (PURA)1,3, DANIEL-CORNELIU LEUCUȚA2*, GABRIEL MARC1, HORIA SIMU3, CRISTINA NASTASĂ1, OVIDIU ONIGA1
1Department of Pharmaceutical Chemistry, “Iuliu Hațieganu” University of Medicine and Pharmacy, 41 Victor Babeș
Street, RO-400012, Cluj-Napoca, Romania
2Department of Medical Informatics and Biostatistics, “Iuliu Hațieganu” University of Medicine and Pharmacy, 6 Louis
Pasteur Street, RO-400012, Cluj-Napoca, Romania
3Department of Ambulance Emergency Service, 55 Horea Street, RO-400202, Cluj-Napoca, Romania
*corresponding author: dleucuta@umfcluj.ro
Download Full Article

Abstract:
The aim of this study was to determine if urapidil, used as a first-line emergency antihypertensive agent represents, in
prehospital interventions, a superior choice if it is administered after other antihypertensive drugs. The paper presents the
results of a retrospective study, based on the medical records of 100 interventions of the Cluj County Ambulance Service,
Romania, for patients with hypertensive crisis. There have been identified significant differences on both intervention time
and time duration until blood pressure normalizes, for the patients that received urapidil was administered as a first-line
antihypertensive, compared to the patients for that received urapidil after other antihypertensive drugs. These preliminary
results can support the use of urapidil as a first-choice antihypertensive agent in prehospital emergency treatment, in
hypertensive outbreak..

Top