EFFICIENCY OF PROPOFOL CO-ADMINISTERED WITH
REMIFENTANIL AND FENTANYL OVER LARYNGEAL MASK
AIRWAY INSERTION
SENEM URFALI1*, BUKET ÇAĞLA ÖZBAKIŞ AKKURT2
1Dortyol State Hospital, Department of Anaesthesiology and Reanimation, Hatay, Turkey
2Mustafa Kemal University, Medical Faculty, Department of Anaesthesiology and Reanimation, Hatay, Turkey
*corresponding author: senemurfali@gmail.com
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Abstract:
In this study we assessed and compared the conditions during insertion of the Laryngeal Mask Airway (LMA) to patients
undergoing minor surgery, who received either remifentanil, fentanyl, or normal saline co-administered with propofol. Ninety
patients with American Society of Anesthesiology (ASA) class-I/II aged from 18 to 60 years undergoing minor surgery were
included in this prospective study. Patients were randomly allocated to receive either normal saline (Group I), fentanyl
1μg/kg (Group II), or remifentanil 1 μg/kg (Group III) over 30 s following induction of anaesthesia with propofol 2.5 μg/kg +
lidocaine 1 μg/kg. LMA insertion conditions including mouth opening, ease of placement, coughing, swallowing,
laryngospasm, airway obstruction and patients’ movement were assessed. Time to eyelash reflex loss, time to successfully
place LMA, number of attempts and haemodynamic variables were also recorded. Demographic data were all similar
between the groups. Heart rate and blood pressure values were lower in remifentanil and fentanyl groups in comparison with
the saline group. Induction rates were found to be the highest in the remifentanil group, followed by fentanyl and saline
groups. Both remifentanil and fentanyl increased the LMA insertion tolerance when co-administered with propofol, with
remifentanil producing slightly better conditions.

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