ANTIBIOTIC SUSCEPTIBILITY TESTING OF SOME PREVOTELLA
STRAINS ISOLATED FROM VESTIBULAR ABSCESSES
ADRIAN BĂNCESCU#, GABRIELA BĂNCESCU#*, ANDREEA DIDILESCU#, MIRCEA HÎRJĂU#
“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
*corresponding author: gabi.bancescu@gmail.com
#All authors contributed equally to this study.
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Abstract:
The aim of this study was to investigate in vitro the antibiotic susceptibility of 53 strains of Prevotella isolated from
vestibular abscesses. The E-test was used for determining the minimum inhibitory concentrations for: benzylpenicillin,
ampicillin, amoxicillin/clavulanic acid, clindamycin and metronidazole. In addition to this, the beta-lactamase production
was detected by the chromogenic cephalosporin test. Most of the strains were susceptible to the tested antibiotics. Twelve
strains were resistant to benzylpenicillin and ampicillin due to the production of beta-lactamase. A single isolate of P. buccae
presented also resistance to clindamycin. In conclusion, the results of this study recommend the prescription of metronidazole
or clindamycin in infections caused by these microorganisms. In case of oral and maxillofacial infections (which are mainly
mixed infections), when antimicrobial treatment is necessary but it is done empirically, it might be proper to choose an
antibiotic active against beta-lactamase producing bacteria too, such as an association of a penicillin with a beta-lactamase
inhibitor.

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