CHEMOTHERAPY-INDUCED CARDIOTOXICITY IN ONCOLOGY
DRUGS INVOLVED AND CLINICAL ASSESSMENT
SIMONA SORANA CĂINAP1,2, VIORICA NAGY1,3, CĂLIN CĂINAP1,3*
1University of Medicine and Pharmacy, 8 Victor Babeş Street, 400012 Cluj-Napoca, Romania
2Emergency County Hospital for Children, 68 Moților Street, 400370, Cluj-Napoca, Romania
3Institute of Oncology “I. Chiricuță”, 34 - 36 Republicii Street, 400015, Cluj-Napoca, Romania
*corresponding author: calincainap@yahoo.co.uk
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Abstract:
Cancer represents an important public health challenge worldwide due to the continuous increase of its incidence. The
general prognosis is more and more favourable with new treatments which allow long survival. Chemotherapeutical
treatments affect the patients, one of the most important issues being represented by cardiotoxicity, which is low responsive
to conventional treatments and finally will determine the survival rate. In this paper we discuss the chemotherapeutical
category of agents incriminated to produce cardiac toxicity and the workup indicated for an early diagnostic.






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