GENETICS OF PSORIASIS SUSCEPTIBILITY AND TREATMENT RESPONSE
VLAD MIHAI VOICULESCU1,2, LILIANA GABRIELA POPA2*, ROXANA SILVIA BUMBACEA1,2, CORNELIA NITIPIR2, CALIN GIURCANEANU1,2
1”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania - Oncologic dermatology and allergology Clinic
2”Elias” University Emergency Hospital, Bucharest, Romania - Dermatology Department
*corresponding author: lilidiaconu@yahoo.com
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Abstract:
Psoriasis is a chronic, recurrent skin disease that has an unknown trigger. Recent development in understanding the disease mechanisms led to the idea that psoriasis has a genetic background on which external triggers act to develop the psoriatic lesions. This review presents the newest information regarding the genetic variants of the psoriatic patients and their influence on disease evolution and treatment response.
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