SMALL LDL: A HELPFUL PARTICLE IN MONITORING PATIENTS
WITH METABOLIC SYNDROME
DANIELA CRISTINA DIMITRIU1#, CORNELIA MIRCEA2#*, CĂTĂLIN PRICOP1,3#, OVIDIU MITU1,4#, RALUCA STĂNESCU1#, MONICA HĂNCIANU2#, ELENA PETRESCU-DĂNILĂ1#
1“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Medicine, 16 Universităţii Street, 700115, Iași,
Romania
2“Grigore T. Popa” University of Medicine and Pharmacy, Faculty of Pharmacy, 16 Universităţii Street, 700115, Iași,
Romania
3“C. I. Parhon” Hospital, 50 Carol I Boulevard, 700503, Iași, Romania
4“Sf. Spiridon” Clinical Emergency Hospital, 1 Independenţei Boulevard, 700111, Iași, Romania
*corresponding author: corneliamircea@yahoo.com
#All authors contributed equally to this work.
DownloadDownload Full Article

Abstract:
Patients with metabolic syndrome have a higher risk of cardiovascular events than healthy subjects. Many studies proved that
plasma lipoprotein levels represent predictive factors for coronary disease. Among lipoproteins, small low density
lipoproteins (sLDL) particles have the highest atherogenic potential. For patients with metabolic syndrome, levels of plasma
sLDL, as compared to other lipid markers that constitute cardiovascular risk factors, and correlated with carotid artery
intima-media thickness (IMT) measured by ultrasound imaging, may represent useful markers for medical and
pharmaceutical practice.






Top