BIOCHEMICAL PARAMETERS CHANGES INDUCED BY LEAD
EXPOSURE
RADU CIPRIAN ŢINCU1*, DANA TOMESCU2,3, LAURENŢIU COMAN3,4, RADU ALEXANDRU MACOVEI1, 3
1Clinical Emergency Hospital Bucharest, Critical Care Toxicology Unit, Bucharest, Romania
2”Fundeni” Clinical Institute Bucharest, Romania
3”Carol Davila” University of Medicine and Pharmacy Bucharest, Romania
4Physiology Department, Faculty of Pharmacy Bucharest, Romania
*corresponding author: r_tincu@yahoo.com
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Abstract:
Lead exposure is still present in adult life, mainly due to work place circumstances, although sustained measures had been
assessed to reduce environmental emissions. The aim of present study was to determine biochemical and haematological
changes in individuals suffering from lead exposure in a particular population group. Patients in lead exposure group had
significantly lower haemoglobin values than controls (p = 0.015), and higher values for gamma-glutamyl transferase and
alkaline phosphatase (p = 0.003 and p = 0.002, respectively).






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