RESULTS IN THE TREATMENT OF CHILDREN’S FACE AND NECK
HEMANGIOMAS AND VASCULAR MALFORMATIONS - WITH
INTRALESIONAL OR PERILESIONAL BLEOMYCIN INJECTION
SEBASTIAN IONESCU1#*, BOGDAN ANDREI1#, MIHAI MOCANU1#, ELENA LICSANDRU1#, IONUT SECHELI1#, MARIAN SECHELI1#, MIRELA VASILESCU2#
1“Marie S. Curie” Emergency Children Hospital - Department of Paediatric Surgery, 20, Bd. C-tin Brancoveanu, sector 4,
Bucharest, 041451, Romania.
2“Univerity of Craiova” – Department of Kinesiology and Sports Medicine, 20, Bd. C-tin Brancoveanu, sector 4, Bucharest,
041451, Romania.
*corresponding author: nsionescu@yahoo.com
#All authors had equal contribution to this research.
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Abstract:
Bleomycin, a polypeptidic antineoplasic antibiotic, was introduced in the treatment of vascular anomalies as sclerosant agent
if injected intralesionally or perilesionally. The study was performed between 2008-2012 on a group of 44 children with
various vascular anomalies of the face and neck, age ranging from 21 days to 15 years old, who were subjected to local
bleomycin injection. For an accurate pursuance and estimation of the efficacy of the treatment, we used the classification of
vascular anomalies suggested by Mulliken and Glowacki in 1982 which allowed us a quick diagnosis. Excellent results
allowed the usage of bleomycin on a large scale in the local treatment of vascular anomalies located on the child’s face and
neck. There were no major side effects or complications by intralesional or perilesional bleomycin administration.

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